Smoking was recently suggested to increase the risk of anal cancer more in premenopausal women than in postmenopausal women. Thus, we used our population-based anal cancer case-control study in Denmark and Sweden to test this hypothesis. Two control groups were used: 1 population control subjects women and men and 2 patients with rectal adenocarcinoma women and men. Odds ratios ORs , calculated from logistic regression analyses, were used as measures of relative risk. All P values are two-sided. Smoking was not statistically significantly associated with anal cancer risk in postmenopausal women or men.
The experts at Moffitt Cancer Center are often asked what causes anal cancer. Unfortunately, as of yet there are no clear-cut answers. Scientists have confirmed that cancer forms when healthy cells undergo changes that cause them to multiply uncontrollably or remain viable long after they should die. The excess cells can bind together and form masses, or tumors, which can potentially invade nearby lymph nodes and spread to distant organs.
Cigarette smoking may be a risk factor for rectal-- but not colon--cancer. Electra Paskett, Ph. After an average follow-up of about 8 years, 1, women were diagnosed with colorectal cancer. Increased colorectal cancer incidence was associated with more cigarettes smoked per day, more years as a smoker, and older age when the women quit smoking.